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Epithalamin had demonstrated bioregulatory activity in earlier experimental gerontology research, and Epitalon was developed to provide a chemically characterized, reproducible molecular tool for investigating its underlying mechanisms

Rectocele is a bulging of the rectum toward the vaginal wall (Mayo Clinic 2014b)

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This may be due to their low molecular mass (the smallest identified protein was 10 kDa) or multicysteine residue modifications, which complicate tryptic peptide analysis

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