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doi: 10.1016/j.jtemb.2007.09.023

Increases in muscle strength ranged from 24-62% depending on the muscle group

Realistically, you're looking at 3 months before you'd see early signs of response, and 6 months for a meaningful assessment

10.1055/s-0042-1755230 Arq Neuropsiquiatr

The updated 2018 diagnostic criteria for PCOS require the presence of at least two of the following three features: (1) oligo/anovulation, (2) clinical and/or biochemical hyperandrogenism, and (3) PCO identified by the presence of 20 antral follicles per ovary on transvaginal ultrasound, with or without increased ovarian volume

Comparison across biofluids further highlighted both opportunity and constraint: while lumbar and ventricular CSF showed strong concordance, plasma profiles diverged substantially, particularly for immune-active pathways such as kynurenine metabolism 67 , indicating that treatment-relevant metabolic states are most directly captured in CSF and only partially reflected in peripheral blood