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Finally, the insertion of Sec at the UGA codon is facilitated through the recognition of a unique selenocysteine insertion sequence (SECIS) present in the three prime untranslated region (3-UTR) of mRNAs of seleno-GPxs by ribosomes with the help of SECIS binding protein (SBP)

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doi: 10.3390/molecules26061592 91 AshourAEAhmedAFKumarAZoheirKMAboul-SoudMAAhmadSFet al

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Loren Pickart, who identified GHK in 1973, published gene-expression analyses suggesting GHK modulates a large number of human genes