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4.1 Central nervous system effects GLP-1R is distributed throughout various regions in the brain, with the highest concentrations being found in the hippocampus and cerebral cortex, areas mainly responsible for cognitive function, memory improvement, and learning (22), as well as in microglia and astrocytes (23)

Published research involving GHK-Cu peptides is limited to non-clinical and investigational settings that explore cellular communication mechanisms, peptidemetal interactions, and molecular signaling models

Clinical trial data from the SURMOUNT programme shows headache reporting drops from 22% at week 4 to approximately 8% by week 12, indicating that most cases resolve as the body adapts to GLP-1 and GIP receptor activation

Instead, experts say the results point to a major blind spot in current research

Most patients return to work the same day