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Sigma-Aldrich) was used, while 0.5 M of the endoplasmic reticulum stress inducer thapsigargin (Sigma-Aldrich) was applied to activate SREBP-2, thereby upregulating genes involved in cholesterol biosynthesis and uptake [22]

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Biomed Pharmacother 148:112759 Gawron VJ, French J, Funke D (2000) An overview of fatigue