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Chem Phys Lipids 164:740758 Salem AF, Wang S, Billet S, Chen J-F, Udompholkul P, Gambini L, Baggio C, Tseng H-R, Posadas EM et al (2018) Reduction of circulating cancer cells and metastases in breast-cancer models by a potent EphA2-agonistic peptidedrug conjugate

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That research base is substantial, spanning several decades and dozens of published studies across multiple tissue systems