The compound reaches Cmax (maximum plasma concentration) within 1530 minutes of subcutaneous injection, binds selectively to ghrelin receptors (specifically the growth hormone secretagogue receptor type 1a, GHS-R1a) on pituitary somatotrophs, and triggers acute growth hormone secretion that peaks 3045 minutes post-injection
Outside of these functions, GLP receptors are also expressed in the human retina and are thought to be involved in the prevention of retinal neurodegeneration, an early event in diabetic retinopathy [23]
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