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This naturally occurring peptide plays a vital role in repairing and regeneration of injured cells and tissues by reducing apoptosis, inflammation, and microbial growth after injury

This growth is mostly attributed to the recent approval of two GLP-1 analogs, semaglutide (Ozempic or Wegovy) and liraglutide (Victoza), for weight management in obese and overweight patients

This shortens the titration period but introduces greater side effect risk

In addition, metformin significantly induced significant late apoptosis in SW837 cells, when compared to vehicle control ( Figure 3D )

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Circulating levels of IGF-1 and certain IGFBPs are critical for the maintenance of glucose homeostasis (64)