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Gault VA, Flatt PR, Harriott P, Mooney MH, Bailey CJ, OHarte FPM

Why GLP-1 Drugs May Affect Digestion

Juhl CB, Hollingdal M, Sturis J, Jakobsen G, Agers H, Veldhuis J, et al

Key Leaders: Tien Lee, MD, Founder & CEO

Mounjaro/Zepbound (tirzepatide), approved dual GLP-1/GIP agonist for type 2 diabetes and obesity Recent Highlights: In April 2026, the FDA approved orforglipron (Foundayo), making it one of the first oral GLP-1 pills that can be taken any time of day and that has no food or water restrictions

By the 1980s, the amino acid and gene sequences of proglucagon (Figure 1) were unraveled