bpc 157 podcast Peptides and BPC-157 for Pain: What's the Deal? FDA panel backs compounded BPC-157,

It is not entirely clear how ALLO, which is a positive allosteric modulator of GABAergic neurotransmission, acts to improve memory function in this patient population, but it has been suggested that stress-induced changes in GABA receptor expression levels are likely to play a role in the etiology of depression

That does not mean BPC-157 has no role around painful joints

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The clinical trial data is specifically reassuring on this point: across six trials involving approximately 900 participants, glucose levels, insulin levels, and markers of insulin sensitivity remained unchanged from baseline

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