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MORE: How to decide if weight-loss drugs are for you "It is a very personal topic for me and for the hundreds of millions of people impacted around the globe who have for years struggled with weight and obesity," Oprah said in a statement

In an exclusive interview with the ABC's Four Corners program for an investigation to air later this year, TGA chief medical advisor, adjunct professor Robyn Langham, explained the regulator's concerns

To qualify for Mounjaro as a weight loss treatment, your BMI must be 30, or 27 if you have at least one weight-related health issue, such as type 2 diabetes, high blood pressure or sleep apnoea

Additionally, a history of acute pancreatitis is flagged as a relative contraindication requiring careful risk-benefit analysis by a physician

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This means you can include carbohydrates in your diet while taking semaglutidethe key is choosing types and amounts that align with your body's new appetite signals