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Used in research on anagen induction, dermal microcirculation and copper-dependent enzymatic systems (lysyl oxidase)

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Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team

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Cost: The cost of injections, especially if administered regularly, can be higher than oral supplements

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