For example, a single 38 g oral dose of MCT (95% C8, 5% C10) given after an overnight fast in a low-carb-high-fat drink improved cognitive performance (memory, but not attention) assessed at the peak of the ketonemia in APOE4-negative AD patients, and the degree of improvement correlated with the HB levels (26)
Proposed pathways include modulation of multiple neurotransmitter systems (influencing serotonin, dopamine, norepinephrine, GABA, glutamate levels), possible involvement of NMDA receptors, alpha-1 adrenergic signaling (e.g., potentiating pineal acetyltransferase activity), inhibition of somatostatin release via dopaminergic routes, reduced ACTH/cortisol for stress buffering, and stimulated growth hormone or somatoliberin secretion
FLEXIBILITY: Quarter-dosing tablets allow for more flexibility in adjusting the dosage
2 This description is repeatedly reproduced online, sometimes in a much stronger form
& Pierre, P
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