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Inflammation Research , 57(5), 205210

Although loss of GOT1, the cytosolic aspartate aminotransferase, kills leukaemia cells upon ETC inhibition (Birsoy et al, 2015), pancreatic ductal adenocarcinoma (PDAC) cells driven by mutant K-Ras rely on both GOT2, for aspartate production, and GOT1, to convert this aspartate into oxaloacetate

A Mediterranean diet does not alter plasma trimethylamine N-oxide concentrations in healthy adults at risk for colon cancer

"We're excited that these data, the first phase 3 data of a next-generation amylin therapy, show promise and we look forward to further investigating Cagrilintide's potential in the dedicated phase 3 RENEW programme," Lange added

C/VEH, n = 7) or CBD (H/CBD, n = 8

Zinc shows a multilayered function in the nucleus, ranging from structural support, enzymatic catalysis, epigenetic and transcriptional regulation, signaling, genome maintenance and redox balance