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However, the extent of this association is unclear since some studies have reported a 7.6-fold increase in the rate of colorectal cancers in acromegalic patients compared with control groups (275), whereas another study has reported as low as twofold increased risk of colorectal cancer in acromegalic patients (286, 287)

The best weight loss results are seen when weight loss medications are combined with intensive lifestyle modification and calorie restriction

Despite longer duration of treatment, no significant weight loss was observed

Meanwhile, Vitamin E protects against free radical damage and helps maintain skin moisture

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