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SELENOP expression considerably overlapped with that in glial fibrillary acidic protein-positive astrocytes and was generally more prominent in white matter

Glycyrrhizin inhibits the metabolism of diosbulbin B (Yang et al., 2024), promotes bile acid efflux by increasing the expression of Nrf2/Farnesoid X Receptor- Bile Salt Export Pump (FXR-BSEP)/Multidrug Resistance-Associated Protein (MRP)2/P-glycoprotein/UDP-glucuronosyltransferase 1A1(UGT1A1), modulates gut microbiota, alleviates inflammation and oxidative stress, and improves diosbulbin B-induced liver injury (Wang et al., 2025)

Subclinical deficiency (low status) of riboflavin without clinical signs may be widespread, including in high-income countries, but usually goes undetected because riboflavin biomarkers are very rarely measured in human studies

ED affects approximately 30 million men in the United States alone, with prevalence increasing dramatically with age

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10.1071/RD23011 41 KermackA