Unreconstituted lyophilized powder stays stable longer but should still be refrigerated for optimal shelf life
Among the rare ocular side effects of GLP-1RAs is non-arteritic anterior ischemic optic neuropathy (NAION), which can cause permanent loss of vision, states the report, Glucagon-like Peptide-1 Receptor Agonists and Ocular Health: Guidance for Optometric Practice. The report was first presented at the 2025 Optometry's Meeting | 5th World Congress of Optometry and is meant to provide critical guidance to doctors of optometry treating patients on GLP-1RAs
Listed contraindications include a personal or family history of medullary thyroid carcinoma and multiple endocrine neoplasia syndrome type 2
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However, although use of these drugs is expanding, it is still hard for healthcare professionals to give patients reliable advice on their use during pregnancy because human safety evidence remains limited