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Am Heart J 2004;148:690-5

Dihexas specific HGF/c-Met mechanism drives synaptogenesis at a structural level potentially creating lasting new neural connections rather than transient neurochemical changes

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A sedentary lifestyle with lowered expression of PGC-1alpha is associated with weight gain, inflammation, and decreased insulin secretion, pathological changes that eventually culminate in T2DM and obesity (191) (Table 3)

Noriega P, Moreno E, Falcn A, Quishpe V, Noriega PC