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It loses its three-dimensional structure and, eventually, its very integrity

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When medication is combined with provider oversight, dietary guidance, and follow-through, patients are often better positioned to stay on track than they would be with willpower alone

Many substances being discussed have enthusiastic supporters as well as critics who point to limited human clinical data

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[DOI] [PubMed] [Google Scholar] Boutron 2014 Boutron I, Altman DG, Hopewell S, VeraBadillo F, Tannock I, Ravaud P