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First, the complex appears to act as a copper transporter, delivering ionic copper to cutaneous cells where it may activate copper-dependent enzymes involved in extracellular-matrix remodeling and angiogenesis

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In addition, genetic damage and neoplastic transformation have been demonstrated in cells co-cultured in vitro with activated phagocytes [149] and the genotoxic effects observed include formation of DNA strand breaks [151], sister chromatid exchange [154] and mutations [155]

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