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The suspension was freeze-thawed 3x at 80C, sonicated 3x 15 s then spun at 12 k RPM for 30 min to pellet the insoluble material

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Clean Safety Profile: Side effects are generally mildfacial flushing, nausea, yawningand serious adverse events are rare when used under controlled research conditions PubMedPubMed

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It tends to improve during the later stages of pregnancy