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Significant yellowing, browning, or any other color change suggests chemical degradation has occurred

Physical signs that may indicate B12 deficiency include a pale or jaundiced (yellowish) complexion due to the breakdown of abnormal red blood cells, a sore or red tongue (glossitis), and mouth ulcers

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Kennedy has echoed those concerns

Subcutaneous and intramuscular delivery allow more of the peptide to enter circulation directly, which is why injection is the more commonly discussed route for recovery and tissue-related goals