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The substitution at position 2 is the functionally important one: it blocks cleavage by dipeptidyl peptidase-4, the protease that degrades native GRF within minutes

However, cellular GSH concentrations vary according to various conditions, which can affect the in vitro function and therapeutic efficacy of MSCs [8]

Changes in cerebral arterial, tissue and venous oxygenation with evoked neural stimulation: implications for hemoglobin-based functional neuroimaging

Mol Ther Nucleic Acids (2020) 19:46881

The information presented reflects clinical trial data available as of the publication date and may not reflect subsequent developments