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While compounding of drugs is allowed when there is a shortage, the FDA determined in 2024 that GLP-1 medications were no longer in short supply

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However, patients should never manually measure semaglutide doses with syringes

Compounded semaglutide products are not FDA approved, and the FDA has issued safety concerns regarding their use and variability in purity, potency, and ingredients

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The main differences between the two treatments are: Available dosage strengths How the treatments are taken How often each treatment is taken (weekly / daily) Wegovy tablets may be prescribed as an adjunct to a reduced-calorie diet and increased physical activity for weight management, including weight loss and weight maintenance, in clinically suitable adults