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While systemic absorption is low, patients on oral anticoagulants or antiplatelet agents should use this product with caution, as there is a theoretical risk of increased bleeding

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CB-839 was added to the final concentrations of 10 nM, 100nM, 1 M, 10 M, and 100 M in triplicate, and the cells were incubated for 72 hours

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In a study with eight poorly controlled T2DM patients who received a liquid meal via a nasogastric tube and exogenous infusion of GLP-1 to achieve plasma levels of about 70 pM, gastric volume remained constant over 2 hours, and plasma glucose returned to normal fasting values within 3 4 hours (152)

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