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Evolution of antioxidant mechanisms: Thiol-Dependent peroxidases and thioltrasferase among prokaryotes

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Apoptosis was mediated by reactive oxygen species (ROS) in cancer cells due to increased oxidative stress, altered mitochondrial membrane permeability (MMP) and inhibition of antioxidant enzymes (superoxide dismutase and glutathione reductase) caused by compounds 65 and 66