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6ae), and tended to increase energy expenditure, fat oxidation and uncoupling protein-1 (UCP-1) expression without altering locomotor activity (Supplementary Fig

Histamine is an immune signalling protein that causes allergies and swelling

Having a physician on board means someone can monitor this response and adjust dosages or strategies as needed

Individuals with liver disease should exercise caution, as rare cases of liver injury have been reported, and berberine undergoes hepatic metabolism

This may involve adjusting both basal insulin and mealtime insulins or taking additional medications like metformin, SGLT-2 inhibitors, or GLP-1s

* Each patient is unique and individual results may vary