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Proper injection technique and provider guidance may help reduce discomfort

We observed that even in the presence of NAC there was production of MetHb in line with packed red cells without treatment

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Participants with renal impairment were excluded if they had previously undergone renal transplantation or had unstable renal function or acute exacerbation of renal disease within 14 days of baseline, as indicated by recent history or worsening of clinical or laboratory signs