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Interestingly, the induction of this fusion is itself dependent on the DHT/AR-stimulated recruitment of three DNA-directed enzymes, activation-induced cytidine deaminase (AID), LINE-1 repeat-encoded ORF2 endonuclease, and topoisomerase II beta (TOP2B), that trigger chromosomal translocation 125,126

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doi:10.1097/WNF.0000000000000063 77 Ghanizadeh, A

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Shiao et al., 2015)

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In 1990, a Canadian endocrinologist first isolated Exendin-4 from a Gila monsters saliva

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and Bataille, D

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