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Pharmacogenetic influence on bupropion bioactivation and clinical outcomes in major depressive disorder

10.1016/j.fct.2018.07.018 55 GuoL.CuiJ.WangH.MedinaR.ZhangS.ZhangX.et al (2021)

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Among these diverse hormone-based therapies, tirzepatide, a dual GLP-1 and GIP receptor agonist with activity biased towards GIP, has demonstrated superior weight-loss efficacy across multiple clinical trials [38]

Some of the drugs mentioned are investigational and have not been approved by the FDA or other regulatory agencies for the uses discussed.