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Timing of Dose: It is recommended to administer PT-141 at least 30 to 45 minutes prior to anticipated sexual activity.In female trials, onset of effect was noted around 30-60 minutes after injection, and similarly men report that it takes about half an hour (sometimes up to an hour) to start feeling the effects

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In particular, fracture risk should be evaluated in populations at risk of fracture, such as postmenopausal women and men older than 50 years

Moreover, the collagen fibers within the treated rats were uniform and evenly spaced out