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It is worth noting that the significantly increased risk of liraglutide is largely driven by the LEADER trial (20) and that of dulaglutide is largely driven by the REWIND test (42), both of which contributed more than 75% of the weight to the overall results

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Choosing between tirzepatide and semaglutide depends on your goals, tolerability, and coverage landscape

Mark the skin with a washable, skin-safe pen, or use time-stamped photos to confirm the site was rested for the full interval before you use it again