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Future studies are warranted to investigate whether DAP, reuterin, and 5-MIAA can reach the ovarian follicle and modulate ferroptosis pathways in granulosa cells, which may have important implications for understanding PCOS-associated follicular dysfunction
It has important roles in the body, contributing to critical processes like energy production, red blood cell formation, DNA synthesis, and neurological function
Iron supplementation should only be initiated after appropriate testing (ferritin, full blood count) confirms deficiency
Additionally, the pathway associated with iron-mediated death in osteoblasts, which utilizes various mechanisms, may represent a potential approach for the clinical management of osteoporosis
doi: 10.1016/S0140-6736(16)00618-8 [DOI] [PMC free article] [PubMed] [Google Scholar] 2.Boyne MS