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They promise an even skin tone by lowering the formation of melanin, which causes lightening in the skin

Food and Drug Administration (FDA): Ozempic (semaglutide) Injection Prescribing Information National Institutes of Health (NIH): Gastrointestinal Side Effects of GLP-1 Receptor Agonists and Clinical Management The New England Journal of Medicine (NEJM): Effects of Semaglutide on Chronic Kidney Disease Progression in Patients with Type 2 Diabetes (The FLOW Trial) American Diabetes Association (ADA): Standards of Care in DiabetesMetabolic Strategies and Renal Safety Profile of Incretin-Based Therapies National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Understanding Acute Kidney Injury: Causes, Risks, and Fluid Balance Protocols

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Phase 2a trial of GSBR-1290 (45mg and 90mg) in 54 T2DM patients over 12 weeks observed significant reduction in HbA1c (45 mg: -1.01%, p=0.008