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They fall instead under the general remit of the Human Medicines Regulations 2012, which is why unlicensed injectable preparations cannot lawfully be supplied for human administration regardless of "research use only" labelling [3][4]

First, all the rats were anesthetized via an intraperitoneal injection of 2% pentobarbital sodium (75 mg/kg), and the hair of the right posterior leg was removed

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For each lab test, we took the average of the observed lab results over the training admissions

At least 6 animals were included in each group and all test subjects were maintained under standard conditions including a 12 hour light/12 hour dark schedule as well as ad libitum access to a standard GLP diet and fresh water