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Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance

Cardiovasc Pathol 20(1):e43e52 Turkoz R (2013) Myocardial protection in pediatric cardiac surgery Artif Organs 37(1):1620 Sznycer-Taub N, Mackie S, Peng YW, Donohue J, Yu S, Aiyagari R, Charpie J (2016) Myocardial oxidative stress in infants undergoing cardiac surgery

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Standard FDA review under PDUFA takes approximately 12 months from NDA submission