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Despite a substantial decrease in the muscle carnitine content (approximately 50%), there was no difference in spontaneous or running-wheel activities between control and cKOt mice (Supplemental Figure 7)

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For example, considering HepG2, Huh7, and Hep3B, even though they are all epithelial liver cancer cells with high expression of HNF4, HepG2 cells have normal expression of wild-type p53, Huh7 cells overexpress a mutant p53, while Hep3B cells are p53 null 65