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In the SURMOUNT-1 trial, tirzepatide 15 mg weekly achieved 20.9% WL over 72 weeks (vs
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High demand, strict approval criteria, cost concerns, and frequent shortages mean insurance plans delay or restrict access to GLP-1sespecially for weight loss or non-diabetic indications
Furthermore, the number of L cells and postprandial plasma GLP-1 secretion decreases in rats fed an obesogenic high-fat diet (HFD) [30]
A cardiovascular prognosis evaluation trial of semaglutide in the treatment of T2DM reported that administration of semaglutide reduced the cardiovascular prognostic risk (110)
For the safety and well-being of pregnant and nursing women, we do not recommend the use of our patches during this period
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