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Your body responds to routine hormone schedules rather than specific clock times

The performance benefit is entirely indirect, mediated through body composition changes that could be achieved through other means

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Despite these temporary setbacks, overeating episodes on semaglutide typically do not trigger the same rapid fat storage response as they would without the medication, because semaglutide continues to lower insulin resistance and improve metabolic flexibility

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In contrast, DIO mice in both groups switched from WD to LD each had significantly increased Proteobacteria relative abundance (represented solely by the genus Parasutterella ) compared to both the WD and the LD controls, suggesting that Proteobacteria relative abundance may be largely influenced by stress or the differences in net energy expenditure (or associated body weight changes) caused by the diet switch