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7% Centella Asiatica calms redness and irritation, while hyaluronic acid and squalane maintain deep hydration

This information guides dosing and indicates when the 30-day shelf life expires

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The mixture was then concentrated under vacuum and the residue was purified by column chromatography on silica gel with a gradient eluent of petroleum ether and ethyl acetate to afford the corresponding product ( 5 )