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It was that knowledge of glucagon sequence, and its biologywhich actually was very critical for my discovery of GLP-1. Originally thought to be simply responsible for triggering insulin secretion by the pancreas, scientists soon discovered that the hormone also inhibits glucagon secretion by the pancreas and delays gastric emptying

Palmer DS, Howrigan DP, Chapman SB, Adolfsson R, Bass N, Blackwood D, et al

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