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In a direct obesity trial, tirzepatide produced greater average weight loss, but both commonly caused gastrointestinal side effects

consider slower titration if gastrointestinal symptoms are problematic Monitoring frequency: More frequent follow-up than in bariatric-naive patients, particularly during dose escalation (every 4-6 weeks initially) Nutritional support: Continued emphasis on protein intake (60-80 grams daily), vitamin/mineral supplementation, and adequate hydration Multidisciplinary coordination: Collaboration between bariatric surgery, endocrinology/obesity medicine, nutrition, and behavioral health providers Contraindications to semaglutide use include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, prior serious hypersensitivity to semaglutide or its components, and pregnancy

However, it's important to remember that cooking techniques and storage conditions can affect the glutathione content in these foods

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Both remain investigational, with no direct head-to-head comparison