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Vildagliptin appears to have a neutral effect, while saxagliptin has a negative effect on bone, increasing osteoclastic activity and decreasing osteocytic and osteoblastic activity in the femur in preclinical studies [108, 109, 109]

Mandrekar P, Bataller R, Tsukamoto H, Gao B

The capping modification of mRNA, which rigorously follows subgenomic mRNA synthesis, is essential for viral translation and propagation, mRNA protection and escape from host immune response 125,126

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