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The mechanism may involve IGF1 LR3s effects on cartilage and synovial tissue, as IGF-1 receptors are present in these tissues and the peptide can influence their body function

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10.1007/s10522-025-10246-7 [Google Scholar] Chung I, Osterwald S, Deeg KI, Rippe K (2012) PML body meets telomere