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Subcutaneous injections of 250 g/kg body weight were delivered into the male wistar rats, resulting in an insulin secretion assay that demonstrates anti-diabetic characteristics through the activation of GLP-1 receptor agonists

These can include:Skin rashes or irritationStomach upset or crampsAllergic reactions Because injections can be risky, the FDA and WHO do not recommend them for skin lightening

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Davies MJ, Aroda VR, Collins BS, Gabbay RA, Green J, Maruthur NM, Rosas SE, Del Prato S, Mathieu C, Mingrone G, Rossing P, Tankova T, Tsapas A, Buse JB

Explore of the beneficial effects of huang-lian-jie-du Decoction on diabetic encephalopathy in db/db mice by UPLC-Q-Orbitrap HRMS/MS based untargeted metabolomics analysis