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Clinical Update 4/22/2022 Toothpaste vs

These anecdotal long-term outcomes suggest that for some EDS patients, prolotherapy serves as a form of maintenance therapy, not a one-time cure, but a reliable way to keep joints functional and pain-controlled by continuously reinforcing the lax ligaments

Psychiatry 137 ZhangY.MaoZ.PanL.LingZ.LiuX.ZhangJ.et al (2018)

Its advice is nonbinding

Red blood cell formation Supports healthy circulation and oxygen transport

In vitro studies demonstrated follicle stem cell activation, and limited clinical data reported increased hair density and thickness at 0.2% concentration (Park et al., 2011)