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Vascular calcification and the gut and blood microbiome in chronic kidney disease patients on peritoneal dialysis: a pilot study

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doi:10.3892/mmr.2019.9946 53

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These metabolic transformations play a crucial role in the pharmacokinetics and bioavailability of curcumin, impacting its therapeutic potential and effectiveness ( FIGURE 2 2.1.1.2 Bioavailability of curcumin Two aromatic ring systems in curcumin include o-methoxy phenolic groups connected by a seven-carbon connector made up of an , -unsaturated -diketone moiety (Karthikeyan et al., 2020)

Similar to the results in the breast cancer cell lines, the liraglutide treatment produced significant demethylation in CDH1 and ADAM33 promoter regions