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Recently, the pharmacotherapy of MASLD mainly focuses on three parts of mechanisms: anti-inflammatory (ASK1 inhibitors), anti-diabetic (GCGR agonists, PPAR agonists), and prevention of lipotoxicity (FXR agonists, FGF21 analogues) (Wei et al., 2024)

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EC 1.11.1.7) was determined by Chance and Maehly's method (Chance and Maehly 1955)

Cloning and chromosomal mapping of the human nonfunctional gene for L-gulono-gamma-lactone oxidase, the enzyme for L-ascorbic acid biosynthesis missing in man