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Regarding organ outcomes, our review indicates that, in high-risk populations, GLP-1RAs are associated with a 12-15% relative risk reduction in MACE and favorable effects on composite renal endpoints

It does this by increasing insulin secretion and reducing the amount of glucose produced by the liver

doi: 10.1111/cen.12766 152 MilnerKMCraigEEThompsonRJVeltmanMWMThomasNSRobertsSet al

TREATMENT TREATMENT Based on treatment(s) chosen during consult , treatment will begin