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This design ensures the glutathione is protected as it travels through the digestive system, enabling it to reach the small intestine intact

PMID:17622482 Cibulka R et al

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West MB, Hill BG, Xuan YT, Bhatnagar A

These results showed that infants were susceptible to APAP-induced hepatotoxicity more than adults because of the reduced glucuronidation activity and increased oxidation

This tissue selectivity for COX inhibition explains the contrasting adverse effects produced by classical NSAIDs, including gastric ulceration and alterations in hemostasis which are not seen with either short- or long-term therapeutic use of APAP